S\u00e1ng nay t\u00f4i \u0111\u1ecdc \u0111\u01b0\u1ee3c m\u1ed9t \u0111i\u1ec1u khi\u1ebfn t\u00f4i suy ngh\u0129 su\u1ed1t c\u1ea3 ng\u00e0y. V\u00e0 t\u00f4i ph\u1ea3i chia s\u1ebb v\u1edbi c\u00e1c b\u1ea1n \u2014 b\u1edfi v\u00ec n\u00f3 thay \u0111\u1ed5i m\u1ed9t ch\u00fat c\u00e1ch t\u00f4i suy ngh\u0129 v\u1ec1 c\u01a1 th\u1ec3. V\u1ec1 cu\u1ed9c s\u1ed1ng. V\u1ec1 l\u00fd do t\u1ea1i sao ch\u00fang ta l\u00e0m nh\u1eefng vi\u1ec7c m\u00ecnh l\u00e0m.
M\u1ed9t b\u00ed \u1ea9n m\u00e0 kh\u00f4ng ai c\u00f3 th\u1ec3 gi\u1ea3i th\u00edch \u0111\u01b0\u1ee3c.
Kho\u1ea3ng 20-30% ng\u01b0\u1eddi l\u1edbn tu\u1ed5i mang \u0111\u1ea7y \u0111\u1ee7 c\u00e1c d\u1ea5u hi\u1ec7u b\u1ec7nh l\u00fd Alzheimer trong n\u00e3o \u2013 m\u1ea3ng amyloid, \u0111\u00e1m r\u1ed1i tau, t\u1ea5t c\u1ea3 nh\u1eefng th\u1ee9 ch\u00fang ta th\u01b0\u1eddng li\u00ean t\u01b0\u1edfng \u0111\u1ebfn c\u0103n b\u1ec7nh n\u00e0y. Nh\u01b0ng h\u1ecd kh\u00f4ng bao gi\u1edd ph\u00e1t tri\u1ec3n c\u00e1c tri\u1ec7u ch\u1ee9ng. Tr\u00ed nh\u1edb c\u1ee7a h\u1ecd v\u1eabn c\u00f2n nguy\u00ean v\u1eb9n. Kh\u1ea3 n\u0103ng nh\u1eadn th\u1ee9c c\u1ee7a h\u1ecd kh\u00f4ng b\u1ecb suy gi\u1ea3m. Hi\u1ec7n t\u01b0\u1ee3ng n\u00e0y \u0111\u01b0\u1ee3c g\u1ecdi l\u00e0 b\u1ec7nh Alzheimer kh\u00f4ng tri\u1ec7u ch\u1ee9ng, v\u00e0 n\u00f3 \u0111\u00e3 l\u00e0m c\u00e1c nh\u00e0 khoa h\u1ecdc b\u1ed1i r\u1ed1i trong nhi\u1ec1u th\u1eadp k\u1ef7. T\u1ea1i sao m\u1ed9t s\u1ed1 b\u1ed9 n\u00e3o l\u1ea1i c\u00f3 th\u1ec3 t\u1ed3n t\u1ea1i \u2013 sau t\u1ea5t c\u1ea3?
Tr\u00ed tu\u1ec7 nh\u00e2n t\u1ea1o \u0111\u00e3 t\u00ecm ra c\u00e2u tr\u1ea3 l\u1eddi
C\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u t\u1ea1i \u0110\u1ea1i h\u1ecdc California, San Diego \u0111\u00e3 s\u1eed d\u1ee5ng tr\u00ed tu\u1ec7 nh\u00e2n t\u1ea1o (AI) \u0111\u1ec3 ph\u00e2n t\u00edch h\u00e0ng ngh\u00ecn m\u1eabu n\u00e3o ng\u01b0\u1eddi v\u00e0 ph\u00e1t hi\u1ec7n ra m\u1ed9t m\u00f4 h\u00ecnh r\u00f5 r\u00e0ng: nh\u1eefng b\u1ed9 n\u00e3o v\u1eabn gi\u1eef \u0111\u01b0\u1ee3c kh\u1ea3 n\u0103ng nh\u1eadn th\u1ee9c d\u00f9 c\u00f3 nh\u1eefng thay \u0111\u1ed5i li\u00ean quan \u0111\u1ebfn b\u1ec7nh Alzheimer cho th\u1ea5y m\u1ed9t m\u00f4 h\u00ecnh gen b\u1ea3o v\u1ec7 \u2014 ho\u1ea1t \u0111\u1ed9ng th\u1ea5p h\u01a1n \u1edf c\u00e1c gen li\u00ean quan \u0111\u1ebfn s\u1ef1 t\u00edch t\u1ee5 protein tau v\u00e0 ho\u1ea1t \u0111\u1ed9ng cao h\u01a1n \u1edf c\u00e1c h\u1ec7 th\u1ed1ng ph\u1ea3n \u1ee9ng c\u0103ng th\u1eb3ng t\u1ebf b\u00e0o.
Trong m\u00f4 h\u00ecnh n\u00e0y, m\u1ed9t lo\u1ea1i protein n\u1ed5i b\u1eadt: Chromogranin A\u2014m\u1ed9t lo\u1ea1i c\u00f4ng t\u1eafc ph\u00e2n t\u1eed c\u00f3 th\u1ec3 quy\u1ebft \u0111\u1ecbnh li\u1ec7u nh\u1eefng thay \u0111\u1ed5i \u1edf n\u00e3o gi\u1ed1ng b\u1ec7nh Alzheimer c\u00f3 th\u1ef1c s\u1ef1 d\u1eabn \u0111\u1ebfn m\u1ea5t tr\u00ed nh\u1edb hay kh\u00f4ng. Khi c\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u lo\u1ea1i b\u1ecf protein n\u00e0y \u1edf chu\u1ed9t, nh\u1eefng con v\u1eadt n\u00e0y ph\u00e1t tri\u1ec3n b\u1ec7nh l\u00fd Alzheimer\u2014nh\u01b0ng v\u1eabn gi\u1eef \u0111\u01b0\u1ee3c tr\u00ed nh\u1edb. V\u00e0 hi\u1ec7u qu\u1ea3 b\u1ea3o v\u1ec7 th\u1eadm ch\u00ed c\u00f2n m\u1ea1nh h\u01a1n \u1edf chu\u1ed9t c\u00e1i, nh\u1eefng con v\u1eadt n\u00e0y c\u0169ng cho th\u1ea5y s\u1ef1 t\u00edch t\u1ee5 tau gi\u1ea3m v\u00e0 c\u1ea5u tr\u00fac kh\u1edbp th\u1ea7n kinh \u0111\u01b0\u1ee3c b\u1ea3o t\u1ed3n.
N\u00f3i c\u00e1ch kh\u00e1c: c\u01a1 th\u1ec3 c\u00f3 nh\u1eefng c\u01a1 ch\u1ebf m\u00e0 ch\u00fang ta h\u1ea7u nh\u01b0 ch\u01b0a b\u1eaft \u0111\u1ea7u hi\u1ec3u \u0111\u01b0\u1ee3c. Nh\u1eefng c\u01a1 ch\u1ebf b\u1ea3o v\u1ec7 b\u1ea9m sinh. Tr\u00ed tu\u1ec7 th\u1ea7m l\u1eb7ng.
Nh\u01b0ng kh\u00f4ng ch\u1ec9 c\u00f3 y\u1ebfu t\u1ed1 di truy\u1ec1n.
\u0110i\u1ec1u khi\u1ebfn tri\u1ec3n v\u1ecdng n\u00e0y c\u00e0ng th\u00eam ph\u1ea7n kh\u1ea3 quan l\u00e0 nh\u1eefng g\u00ec c\u00e1c nghi\u00ean c\u1ee9u kh\u00e1c ch\u1ec9 ra song song. B\u1edfi v\u00ec kh\u00f4ng ch\u1ec9 protein v\u00e0 gen quy\u1ebft \u0111\u1ecbnh qu\u00e1 tr\u00ecnh l\u00e3o h\u00f3a c\u1ee7a n\u00e3o b\u1ed9.
M\u1ed9t nghi\u00ean c\u1ee9u m\u1edbi t\u1eeb \u0110\u1ea1i h\u1ecdc Miami \u0111\u00e3 theo d\u00f5i nh\u1eefng ng\u01b0\u1eddi tr\u01b0\u1edfng th\u00e0nh duy tr\u00ec ho\u1eb7c c\u1ea3i thi\u1ec7n th\u00f3i quen l\u1ed1i s\u1ed1ng c\u1ee7a h\u1ecd t\u1eeb khi c\u00f2n tr\u1ebb - v\u00e0 ph\u00e1t hi\u1ec7n ra r\u1eb1ng h\u1ecd c\u00f3 kh\u1ea3 n\u0103ng nh\u1eadn th\u1ee9c t\u1ed1t h\u01a1n, s\u1ee9c \u0111\u1ec1 kh\u00e1ng c\u1ee7a n\u00e3o b\u1ed9 cao h\u01a1n v\u00e0 c\u1ea5u tr\u00fac n\u00e3o kh\u1ecfe m\u1ea1nh h\u01a1n sau n\u00e0y trong cu\u1ed9c s\u1ed1ng. Trong s\u1ed1 c\u00e1c y\u1ebfu t\u1ed1 ri\u00eang l\u1ebb, ho\u1ea1t \u0111\u1ed9ng th\u1ec3 ch\u1ea5t v\u00e0 ch\u1ebf \u0111\u1ed9 \u0103n u\u1ed1ng l\u00e0 nh\u1eefng y\u1ebfu t\u1ed1 b\u1ea3o v\u1ec7 nh\u1ea5t qu\u00e1n nh\u1ea5t. Nh\u01b0ng c\u00e1c m\u1ed1i quan h\u1ec7 x\u00e3 h\u1ed9i c\u0169ng \u0111\u00f3ng m\u1ed9t vai tr\u00f2 quan tr\u1ecdng.
Nghi\u00ean c\u1ee9u POINTER quy m\u00f4 l\u1edbn c\u1ee7a M\u1ef9 \u2014 nghi\u00ean c\u1ee9u \u0111\u1ea7u ti\u00ean thu\u1ed9c lo\u1ea1i n\u00e0y \u2014 \u0111\u00e3 ch\u1ec9 ra r\u1eb1ng m\u1ed9t bi\u1ec7n ph\u00e1p can thi\u1ec7p l\u1ed1i s\u1ed1ng d\u1ec5 ti\u1ebfp c\u1eadn v\u00e0 b\u1ec1n v\u1eefng th\u1ef1c s\u1ef1 c\u00f3 th\u1ec3 b\u1ea3o v\u1ec7 ch\u1ee9c n\u0103ng nh\u1eadn th\u1ee9c \u1edf ng\u01b0\u1eddi l\u1edbn tu\u1ed5i c\u00f3 nguy c\u01a1 cao. K\u1ebft qu\u1ea3 nh\u1ea5t qu\u00e1n b\u1ea5t k\u1ec3 tu\u1ed5i t\u00e1c, gi\u1edbi t\u00ednh v\u00e0 ngu\u1ed3n g\u1ed1c d\u00e2n t\u1ed9c.
Nghi\u00ean c\u1ee9u cho th\u1ea5y ch\u1ebf \u0111\u1ed9 \u0103n \u0110\u1ecba Trung H\u1ea3i, B\u1eafc \u00c2u v\u00e0 \u0103n chay h\u1ed7 tr\u1ee3 kh\u1ea3 n\u0103ng ph\u1ee5c h\u1ed3i nh\u1eadn th\u1ee9c. T\u1eadp th\u1ec3 d\u1ee5c \u2013 c\u1ea3 aerobic v\u00e0 r\u00e8n luy\u1ec7n s\u1ee9c m\u1ea1nh \u2013 c\u1ea3i thi\u1ec7n t\u00ednh d\u1ebbo dai c\u1ee7a th\u1ea7n kinh. Gi\u1ea5c ng\u1ee7 \u0111\u00f3ng vai tr\u00f2 thanh l\u1ecdc trao \u0111\u1ed5i ch\u1ea5t, n\u00e3o b\u1ed9 th\u1ef1c s\u1ef1 lo\u1ea1i b\u1ecf c\u00e1c ch\u1ea5t th\u1ea3i trong khi ch\u00fang ta ng\u1ee7. V\u00e0 c\u0103ng th\u1eb3ng m\u00e3n t\u00ednh d\u1eabn \u0111\u1ebfn teo (ch\u1ebft) h\u1ed3i h\u1ea3i m\u00e3 \u2013 trung t\u00e2m tr\u00ed nh\u1edb c\u1ee7a n\u00e3o b\u1ed9. <\/p>\n\n\n\n
Th\u1ee9 T\u01b0 th\u1ef1c s\u1ef1 c\u00f3 \u00fd ngh\u0129a g\u00ec?
T\u00f4i ngh\u0129 v\u1ec1 t\u1ea5t c\u1ea3 nh\u1eefng \u0111i\u1ec1u n\u00e0y khi n\u1ea5u \u0103n v\u00e0o th\u1ee9 T\u01b0. L\u00ean k\u1ebf ho\u1ea1ch cho c\u00e1c b\u1eefa \u0103n trong tu\u1ea7n. \u0110\u00f3 l\u00e0 s\u1ef1 quan t\u00e2m \u2014 \u0111\u1ebfn b\u1ed9 n\u00e3o l\u00e0m vi\u1ec7c ch\u0103m ch\u1ec9 cho t\u00f4i m\u1ed7i ng\u00e0y.
K\u00edch th\u00edch nh\u1eadn th\u1ee9c \u2014 h\u1ecdc h\u1ecfi nh\u1eefng \u0111i\u1ec1u m\u1edbi, s\u00e1ng t\u1ea1o, tham gia \u2014 c\u00f3 li\u00ean quan \u0111\u1ebfn kh\u1ea3 n\u0103ng ch\u1ed1ng l\u1ea1i b\u1ec7nh Alzheimer. C\u01a1 ch\u1ebf t\u1ebf b\u00e0o v\u00e0 ph\u00e2n t\u1eed ch\u00ednh x\u00e1c v\u1eabn ch\u01b0a \u0111\u01b0\u1ee3c hi\u1ec3u \u0111\u1ea7y \u0111\u1ee7, nh\u01b0ng m\u1ed1i li\u00ean h\u1ec7 l\u00e0 r\u00f5 r\u00e0ng.<\/p>\n\n\n\n
\u0110i\u1ec1u \u0111\u00f3 c\u00f3 ngh\u0129a l\u00e0 nh\u1eefng g\u00ec b\u1ea1n l\u00e0m h\u00f4m nay \u0111\u1ec1u quan tr\u1ecdng. S\u1ef1 v\u1eadn \u0111\u1ed9ng. Th\u1ee9c \u0103n. Gi\u1ea5c ng\u1ee7. S\u1ef1 s\u00e1ng t\u1ea1o. C\u1ed9ng \u0111\u1ed3ng. Kh\u00f4ng ph\u1ea3i v\u00ec b\u1ea1n s\u1ee3 h\u00e3i t\u01b0\u01a1ng lai \u2014 m\u00e0 v\u00ec b\u1ea1n y\u00eau cu\u1ed9c s\u1ed1ng hi\u1ec7n t\u1ea1i.
N\u00e3o b\u1ed9 c\u1ee7a b\u1ea1n c\u00f3 s\u1ee9c m\u1ea1nh l\u1edbn h\u01a1n ch\u00fang ta t\u01b0\u1edfng. Nghi\u00ean c\u1ee9u \u0111ang ch\u1ee9ng minh \u0111i\u1ec1u \u0111\u00f3.<\/p>\n\n\n\n
C\u00f2n ch\u00fang ta? Ch\u00fang ta l\u1ef1a ch\u1ecdn cung c\u1ea5p cho n\u00f3 ngu\u1ed3n dinh d\u01b0\u1ee1ng v\u00e0 \u0111i\u1ec1u ki\u1ec7n s\u1ed1ng ph\u00f9 h\u1ee3p. \ud83c\udf31<\/p>\n\n\n\n
\u2014 Maria, Amaelle Life \u2013 Th\u1ee9 T\u01b0 tuy\u1ec7t v\u1eddi<\/p>\n\n\n\n
T\u00e1i b\u00fat:<\/p>\n\n\n\n
Tau l\u00e0 m\u1ed9t lo\u1ea1i protein th\u01b0\u1eddng gi\u00fap gi\u1eef cho "khung" b\u00ean trong c\u1ee7a t\u1ebf b\u00e0o th\u1ea7n kinh \u1ed5n \u0111\u1ecbnh \u2014 gi\u1ed1ng nh\u01b0 \u0111\u01b0\u1eddng ray xe l\u1eeda gi\u1eef cho c\u00e1c \u0111o\u1ea1n \u0111\u01b0\u1eddng ray li\u00ean k\u1ebft v\u1edbi nhau.
Trong b\u1ec7nh Alzheimer, protein tau b\u1eaft \u0111\u1ea7u v\u00f3n c\u1ee5c m\u1ed9t c\u00e1ch b\u1ea5t th\u01b0\u1eddng v\u00e0 t\u1ea1o th\u00e0nh c\u00e1c b\u00fai r\u1ed1i b\u00ean trong t\u1ebf b\u00e0o th\u1ea7n kinh \u2014 \u0111\u00e2y l\u00e0 \u0111i\u1ec1u \u0111\u01b0\u1ee3c g\u1ecdi l\u00e0 c\u00e1c b\u00fai r\u1ed1i tau trong nghi\u00ean c\u1ee9u (v\u00e0 "b\u00fai r\u1ed1i" trong m\u1ed9t s\u1ed1 b\u00e0i vi\u1ebft). Nh\u1eefng b\u00fai r\u1ed1i n\u00e0y c\u1ea3n tr\u1edf qu\u00e1 tr\u00ecnh v\u1eadn chuy\u1ec3n ch\u1ea5t dinh d\u01b0\u1ee1ng v\u00e0 t\u00edn hi\u1ec7u c\u1ee7a t\u1ebf b\u00e0o, v\u00e0 c\u00e1c t\u1ebf b\u00e0o th\u1ea7n kinh b\u1eaft \u0111\u1ea7u ch\u1ebft.
S\u1ef1 t\u00edch t\u1ee5 protein Tau = khi c\u00e1c c\u1ee5m protein n\u00e0y t\u1eadp trung v\u00e0 lan r\u1ed9ng trong n\u00e3o.
\u0110i\u1ec1u th\u00fa v\u1ecb trong nghi\u00ean c\u1ee9u m\u1edbi n\u00e0y l\u00e0 n\u00e3o b\u1ed9 \u0111\u01b0\u1ee3c b\u1ea3o v\u1ec7 b\u1edfi Chromogranin A cho th\u1ea5y s\u1ef1 t\u00edch t\u1ee5 tau \u00edt h\u01a1n \u2014 m\u1eb7c d\u00f9 c\u00e1c m\u1ea3ng amyloid (d\u1ea5u hi\u1ec7u kh\u00e1c c\u1ee7a b\u1ec7nh Alzheimer) v\u1eabn c\u00f2n. Do \u0111\u00f3, c\u00f3 v\u1ebb nh\u01b0 qu\u00e1 tr\u00ecnh tau \u0111\u1eb7c bi\u1ec7t quan tr\u1ecdng \u0111\u1ed1i v\u1edbi vi\u1ec7c c\u00e1c tri\u1ec7u ch\u1ee9ng c\u00f3 th\u1ef1c s\u1ef1 x\u1ea3y ra hay kh\u00f4ng.
<\/p>","protected":false},"excerpt":{"rendered":"
S\u00e1ng nay t\u00f4i \u0111\u1ecdc \u0111\u01b0\u1ee3c m\u1ed9t \u0111i\u1ec1u khi\u1ebfn t\u00f4i suy ngh\u0129 su\u1ed1t c\u1ea3 ng\u00e0y. V\u00e0 t\u00f4i ph\u1ea3i chia s\u1ebb v\u1edbi c\u00e1c b\u1ea1n \u2014 b\u1edfi v\u00ec n\u00f3 thay \u0111\u1ed5i m\u1ed9t ch\u00fat c\u00e1ch t\u00f4i suy ngh\u0129 v\u1ec1 c\u01a1 th\u1ec3. V\u1ec1 cu\u1ed9c s\u1ed1ng. V\u1ec1 l\u00fd do t\u1ea1i sao ch\u00fang ta l\u00e0m nh\u1eefng vi\u1ec7c ch\u00fang ta l\u00e0m. B\u00ed \u1ea9n m\u00e0 kh\u00f4ng ai c\u00f3 th\u1ec3 gi\u1ea3i th\u00edch \u0111\u01b0\u1ee3c: Kho\u1ea3ng 20-30% ng\u01b0\u1eddi l\u1edbn tu\u1ed5i mang b\u1ec7nh l\u00fd Alzheimer ho\u00e0n ch\u1ec9nh trong n\u00e3o\u2026<\/p>","protected":false},"author":5196,"featured_media":7238,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"advanced_seo_description":"","jetpack_seo_html_title":"","jetpack_seo_noindex":false,"jetpack_seo_schema_type":"","_kad_post_transparent":"","_kad_post_title":"","_kad_post_layout":"","_kad_post_sidebar_id":"","_kad_post_content_style":"","_kad_post_vertical_padding":"","_kad_post_feature":"","_kad_post_feature_position":"","_kad_post_header":false,"_kad_post_footer":false,"_kad_post_classname":"","_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"page_builder":"","_jetpack_feature_clip_id":0,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_post_was_ever_published":false},"categories":[50],"tags":[92,91,90],"class_list":["post-7234","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-otrolig-onsdag","tag-alzeimer","tag-halsa","tag-hjarna"],"jetpack_sharing_enabled":true,"jetpack_featured_media_url":"https:\/\/amaelle.life\/wp-content\/uploads\/2026\/04\/IMG_2286.jpeg","_links":{"self":[{"href":"https:\/\/amaelle.life\/vi\/wp-json\/wp\/v2\/posts\/7234","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/amaelle.life\/vi\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/amaelle.life\/vi\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/amaelle.life\/vi\/wp-json\/wp\/v2\/users\/5196"}],"replies":[{"embeddable":true,"href":"https:\/\/amaelle.life\/vi\/wp-json\/wp\/v2\/comments?post=7234"}],"version-history":[{"count":3,"href":"https:\/\/amaelle.life\/vi\/wp-json\/wp\/v2\/posts\/7234\/revisions"}],"predecessor-version":[{"id":7240,"href":"https:\/\/amaelle.life\/vi\/wp-json\/wp\/v2\/posts\/7234\/revisions\/7240"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/amaelle.life\/vi\/wp-json\/wp\/v2\/media\/7238"}],"wp:attachment":[{"href":"https:\/\/amaelle.life\/vi\/wp-json\/wp\/v2\/media?parent=7234"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/amaelle.life\/vi\/wp-json\/wp\/v2\/categories?post=7234"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/amaelle.life\/vi\/wp-json\/wp\/v2\/tags?post=7234"}],"curies":[{"name":"trang web","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}